ea0056p796 | Pituitary - Clinical | ECE2018
Malicka Joanna
, Malicki Dariusz
, Kurowska Maria
, Potembska Emilia
, Tarach Jerzy S.
Background: Prolonged exposure to excessive concentrations of GH and IGF-1 in acromegaly continues to affect patientsÂ’ appearance and negatively influences their self-evaluation, personal relations and morbidity. Besides chronic GH/IGF-1 excess could be deleterious to the brain through many mechanisms.Objectives: The aim of the study was to evaluate the influence of acromegaly on the prevalence and the severity of depressive symptoms in patients wit...